[B069] 转化医学检索

post
https://connect.zhihuiya.com/synapse/translational/medicine/search
在体验中心中试用

通过药物、靶点、适应症、机构、主题、转化阶段、期刊、会议等字段,获取转化医学相关数据

以下查询条件必须存在一个或多个:drug、target、disease、organizations、mechanism、drugType、keywords、subject、translationStage、publicationDate、journal、conference。keywords 参数最多支持20个值。conference的值获取可以参考产品,会议与年份之间需要用空格隔开。

请求参数

此 API 接口支持的参数列表

名称类型示例描述
conference
array[ "WCLC 2025", "AACR 2024", "ADA 2025" ]
会议名称,参考产品会议名称
disease
array[ "f98fd32baa8447119bb87f84093b925c", "74d974da49ba407195b38595a0aff704" ]
适应症
drug
objectPlease check the form: DrugFilterAndCondition
药物,condition默认为OR,支持AND
condition
stringOR
条件,OR或AND
value
array[ "c7a2671dc0574f19bc42d557eca3906f", "9ae626b75273433f8f4203ee3f7aa181" ]
值列表
drug_type
array[ "6718bf09d6024f4db4f309a4cc791cf6", "6be383aaee904d2b8321e2d1fdacf8bb" ]
药物类型
journal
array[ "N Engl J Med", "Nat Med" ]
期刊名称,Nature | Science | Cell | Lancet | N Engl J Med | Proc Natl Acad Sci U S A | Nat Commun | Nat Genet | Nat Med | Sci Transl Med | J Med Chem
keywords
objectPlease check the form: KeywordsFilterAndCondition
关键词
condition
stringOR
条件,OR或AND
value
array[ "Sacituzumab govitecan", "Oral" ]
值列表
limit
integer<int64>10
返回条数,默认10。 offset + limit <= 10000, limit最大设置100
mechanism
array[ "cf1cf8ea0f9b80ee88876a3324ceac99", "888b99dda6a62ef2551937c34e253e9c" ]
作用机制
offset
integer<int64>-
偏移量,默认0
organizations
array[ "5c1eb05d43334b6d6d7973ee3073b7b4", "52aee12631589b24dca3ae62de8a0886" ]
机构
publication_date
objectPlease check the form: PublicationDateFilter
发布时间,1:1周内 | 2:1个月内 | 3:1年内 | 4:3年内 | 5:自定义
end_date
string2024-12-31
结束时间(自定义时使用)
start_date
string2024-01-01
开始时间(自定义时使用)
type
integer<int32>4
时间范围类型,1:1周内 | 2:1个月内 | 3:1年内 | 4:3年内 | 5:自定义
sort
arrayPlease check the form: SortField
字段排序,field支持: PUB_DT, order支持desc, asc (默认desc)
field
stringPUB_DT
排序字段,支持: PUB_DT
order
stringdesc
排序顺序,desc或asc,默认desc
subject
array[ "3期临床研究" ]
主题/标签,流行病学|致病机理|靶点|生物标志物|结构生物学|药物发现/临床前|1期临床研究|1/2期临床研究|2期临床研究|2/3期临床研究|3期临床研究|上市后研究|真实世界研究|新技术
target
objectPlease check the form: TargetFilterAndCondition
靶点,condition默认为OR,支持AND
condition
stringOR
条件,OR或AND
value
array[ "d8cdb9ce63174077a9ef868b39bf3421", "c385dcba5fea4e97bf02bc256757613a" ]
值列表
translation_stage
array[ "T2" ]
转化阶段,T0 | T1 | T2 | T3

响应结构

API 响应数据的结构说明

字段名类型示例描述
data
object-
响应数据
items
arrayPlease check the form:TranslationalMedicineSearchDataDetail
查询结果
drugs
arrayPlease check the form: CommonDrug
药物
drug_id
stringe82b83b42eba4e5ea3f26f8e06081a5a
药物ID
display_name
array[ { "lang": "EN", "name": "Ranibizumab (Genentech)" }, { "lang": "CN", "name": "雷珠单抗" } ]
药物名称,引用“CommonName”
lang
stringEN
语言
name
stringRanibizumab (Genentech)
药物、靶点、机构、适应症、国家/地区、字典、作用机制 名称
title
stringNovel Biomarker Discovery in Cancer Research
标题
disease
arrayPlease check the form: CommonDisease
适应症
disease_id
string06a9082fe1ec4c97bea31d888b9cfdce
适应症ID
display_name
array[ { "lang": "EN", "name": "Uveitic Macular Edema" }, { "lang": "CN", "name": "葡萄膜炎黄斑水肿" } ]
适应症名称,引用“CommonName”
journal
objectPlease check the form: CommonNorIdName
期刊
name
stringAcute Kidney Injury
名称
normalized_id
string87bfaf037f8e60c9e25595cd98bb27e4
标准ID
subject
arrayPlease check the form: CommonNorIdName
主题
targets
arrayPlease check the form: CommonTarget
靶点
target_id
string1c2067e5ab054a8995f73efcfcf56207
靶点ID
short_name
array[ { "lang": "EN", "name": "VEGF" } ]
靶点简称,引用“CommonName”
display_name
array[ { "lang": "EN", "name": "Vascular endothelial growth factor" }, { "lang": "CN", "name": "血管内皮生长因子" } ]
靶点全称,引用“CommonName”
drug_type
arrayPlease check the form: CommonDictionary
药物类型
display_name
array[ { "lang": "EN", "name": "Autologous CAR-T" }, { "lang": "CN", "name": "自体CAR-T" } ]
字典名称
normalized_id
string2fbfdb3e92d942c48cbb0adb79f23526
字典ID
technology
arrayPlease check the form: CommonNorIdName
技术
source_info
arrayPlease check the form: TranslationalMedicineSourceInfo
来源信息
code
stringNATURE-2024-001
编码
source
stringNature
来源
patsnap_id
stringpatsnap_1234567890
PatSnap ID
source_url
stringhttps://www.nature.com/articles/s41586-024-01234-5
来源URL
normalized_source_id
string368cf867-f484-430e-9530-44f5cccdd973
标准化来源ID
normalized_source_category
stringJournal
标准化来源类别
organization
arrayPlease check the form: CommonOrganization
机构
display_name
array[ { "lang": "EN", "name": "Roche Holding AG" }, { "lang": "CN", "name": "罗氏" } ]
机构名称,引用“CommonName”
organization_id
string87bfaf037f8e60c9e25595cd98bb27e4
机构ID
mechanism_action
arrayPlease check the form: CommonMechanismAction
作用机制
short_name
array[ { "lang": "EN", "name": "KRAS G12C inhibitors" }, { "lang": "CN", "name": "KRAS G12C抑制剂" } ]
作用机制简称
display_name
array[ { "lang": "EN", "name": "GTPase KRas G12C inhibitors" }, { "lang": "CN", "name": "KRAS G12C突变抑制剂" } ]
作用机制 名称
mechanism_id
string27c0848a265e4332836e10d0e8202b4c
作用机制ID
publication_date
string2024-01-15
出版日期
translation_stage
arrayPlease check the form: CommonNorIdName
转化阶段
translational_medicine_id
stringtm_1234567890abcdef
转化医学ID
limit
integer<int64>10
返回条数
total
integer<int64>10
总量
offset
integer<int64>-
偏移量
status
必填
booleanfalse
状态
error_msg
stringThe request parameter format is incorrect!
错误信息
error_code
必填
integer0
错误代码

成功响应示例

成功调用 API 的响应示例

JSON
{
  "data": {
    "items": [
      {
        "drugs": [
          {
            "drug_id": "e82b83b42eba4e5ea3f26f8e06081a5a",
            "display_name": [
              {
                "lang": "EN",
                "name": "Ranibizumab (Genentech)"
              }
            ]
          }
        ],
        "title": "Novel Biomarker Discovery in Cancer Research",
        "disease": [
          {
            "disease_id": "06a9082fe1ec4c97bea31d888b9cfdce",
            "display_name": [
              {
                "lang": "EN",
                "name": "Ranibizumab (Genentech)"
              }
            ]
          }
        ],
        "journal": {
          "name": "Acute Kidney Injury",
          "normalized_id": "87bfaf037f8e60c9e25595cd98bb27e4"
        },
        "subject": [
          {
            "name": "Acute Kidney Injury",
            "normalized_id": "87bfaf037f8e60c9e25595cd98bb27e4"
          }
        ],
        "targets": [
          {
            "target_id": "1c2067e5ab054a8995f73efcfcf56207",
            "short_name": [
              {
                "lang": "EN",
                "name": "Ranibizumab (Genentech)"
              }
            ],
            "display_name": [
              {
                "lang": "EN",
                "name": "Ranibizumab (Genentech)"
              }
            ]
          }
        ],
        "drug_type": [
          {
            "display_name": [
              {
                "lang": "EN",
                "name": "Ranibizumab (Genentech)"
              }
            ],
            "normalized_id": "2fbfdb3e92d942c48cbb0adb79f23526"
          }
        ],
        "technology": [
          {
            "name": "Acute Kidney Injury",
            "normalized_id": "87bfaf037f8e60c9e25595cd98bb27e4"
          }
        ],
        "source_info": [
          {
            "code": "NATURE-2024-001",
            "source": "Nature",
            "patsnap_id": "patsnap_1234567890",
            "source_url": "https://www.nature.com/articles/s41586-024-01234-5",
            "normalized_source_id": "368cf867-f484-430e-9530-44f5cccdd973",
            "normalized_source_category": "Journal"
          }
        ],
        "organization": [
          {
            "display_name": [
              {
                "lang": "EN",
                "name": "Ranibizumab (Genentech)"
              }
            ],
            "organization_id": "87bfaf037f8e60c9e25595cd98bb27e4"
          }
        ],
        "mechanism_action": [
          {
            "short_name": [
              {
                "lang": "EN",
                "name": "Ranibizumab (Genentech)"
              }
            ],
            "display_name": [
              {
                "lang": "EN",
                "name": "Ranibizumab (Genentech)"
              }
            ],
            "mechanism_id": "27c0848a265e4332836e10d0e8202b4c"
          }
        ],
        "publication_date": "2024-01-15",
        "translation_stage": [
          {
            "name": "Acute Kidney Injury",
            "normalized_id": "87bfaf037f8e60c9e25595cd98bb27e4"
          }
        ],
        "translational_medicine_id": "tm_1234567890abcdef"
      }
    ],
    "limit": 10,
    "total": 10,
    "offset": 0
  },
  "status": true,
  "error_code": 0
}

错误码

此接口可能返回的错误码列表

业务错误码

错误码描述
68300004请求参数异常!
68300005查询Api失败!
68300006解析基本存取错误!
68300007存在错误的请求!
68300008服务中断异常,请稍后再试!
68300010文件不符合上传规范!

平台错误码

错误码描述
67200000API整体限流错误!
67200001API整体限流错误!
67200002当前调用速率过快,超过当前配置限制QPS!
67200003申请token的key和secret传参不正确或者客户端已被禁用!
67200004请求的接口无权限请联系我们的支持人员!
67200005账户余额/调用次数不足!
67200006客户端超过开通有效期!
67200007当前调用超过当天配置使用额度!
67200008请检查query参数中必填的apikey是否传输!
67200009apikey与所传的bearerToken不匹配,请检查是否使用在有效期内的token!
67200012请求不合法!
67200100当前服务器状态正忙,请求响应超时!
67200101当前请求的Api不存在请检查请求Path!

HTTP 状态码

状态码描述
0请求成功
201Created
401Unauthorized
403Forbidden
404Not Found

性能指标

此接口的预期性能特征

正常响应时间

5000 ms

最大响应时间

10000 ms